Efficacy of SLN Block for Chronic Cough
Efficacy of SLN Block for Chronic Cough
This is a research study to find out if superior laryngeal nerve blocks are an effective way to reduce cough when compared to placebo (a substance without any medical value). Eligibility for the study include the following: age >18, cough history suggestive that the nerve to the voice box is overactive, non-smoker, Patients will be followed over time and assigned to either the treatment or placebo group at random. The treatment would be four superior laryngeal nerve blocks and the placebo would be four saline injections (the inactive substance). Study team will measure if the injection improved cough and ask patients to keep a log of symptoms and fill out questionnaires at each visit. After the four injections, patients will follow up in 3 months to see if cough has returned and if so, how severe the cough is.
Study Type: Interventional (Clinical Trial)
Estimated Enrollment: 50 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single (Participant)
Primary Purpose: Treatment
Official Title: Efficacy of Superior Laryngeal Nerve Block for Chronic Cough
Actual Study Start Date: July 22, 2020
Estimated Primary Completion Date: December 30, 2022
Estimated Study Completion Date: December 30, 2022
Arm:
- Experimental: Steroid-Lidocaine Mixture
- Placebo Comparator: Placebo
| Category | Value |
|---|---|
| Study type(s) | Interventional |
| Estimated enrolment | 50 |
| Actual Study start date | 22 July 2020 |
| Estimated Study Completion Date | 30 December 2022 |