Glycerol

Glycerol 2g Suppositories

Each suppository contains 1400mg GlycerolFor full list of excipients, see 6.1.

Amber coloured suppository, of nominal weight 2g intended for rectal administration.

For occasional use as a stimulant laxative for the treatment of constipation.

For rectal use

Children

One 2g suppository, to aid insertion the suppository tip should be moistened with water before use.

• Hypersensitivity to the active substance(s) or to any of the excipients.• The product is contraindicated if there is intestinal obstruction or blockage.

The product is intended for occasional use only. Prolonged or excessive use of the product is not recommended as this may cause diarrhoea. Use of this product may interfere with glucose control in diabetic patients. If symptoms persist consult a doctor.

No interaction studies have been performed

No evidence of harmful affects available. However, best avoided during the first trimester of pregnancy. May be used during breast feeding.

None stated.

Use of the product may occasionally cause abdominal cramps. Glycerol can cause irritation when given rectally.

Overdosage via rectal route is unlikely. However, if ingested treat symptomatically.

ATC code A06AX01

Glycerol is commonly classified as an osmotic laxative but may act additionally or alternatively by promoting peristalsis and evacuation of the lower bowel by virtue of a mild irritant effect. Glycerol suppositories possess also lubricating and faecal softening actions.

Glycerol following rectal administration is poorly absorbed.

There are no preclinical data of relevance to the prescriber, which are additional to those already included in other sections of the SmPC

Gelatin Purified Water

Not applicable

3 years

Store below 25°C in a dry place

Heat sealed cavities composed of Polyvinyl Chloride (PVC) coated with Polyvinylidene Chloride (PVDC) and laminated with polyethylene (PE), each containing 1x 4g suppository in strips of 6. The strips and a patient leaflet are packed into cardboard cartons. Pack size available: 12 x 4g.

Wash hands before opening individual packaging. The suppository is shaped for rectal insertion, ensure the tip of the suppository is inserted first. The tip should be moistened with a little cold water to aid insertion.

Martindale Pharmaceuticals Ltd.Bampton Road, Romford, RM3 8UGUnited Kingdom

PL 00156/0120

13/07/2009

02/10/2013