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Consensus on diagnosis and management of Cushing's disease: a guideline update

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Last updated:19th Oct 2021
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Consensus on diagnosis and management of Cushing's disease: a guideline update - The Pituitary Society


Cushing’s disease (CD) requires accurate diagnosis, careful treatment selection, and long-term management to optimize patient outcomes. The Pituitary Society convened a Consensus Workshop comprising more than 50 academic researchers and clinical experts to discuss the application of recent evidence to clinical practice. In advance of the virtual meeting, recent data on screening and diagnosis; surgery, medical and radiation therapy; and disease- and treatment-related complications of CD were critically summarized in recorded lectures that were reviewed by all participants. During the meeting, concise summaries of the recorded lectures were presented, followed by small group breakout discussions. Consensus opinions from each group were collated into a draft document, which was reviewed and approved by all participants. Recommendations regarding use of laboratory tests, imaging, and treatment options are presented, along with algorithms for diagnosis of Cushing’s syndrome and management of CD. Topics considered most important to address in future research are also identified.


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