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Diagnostic and Treatment Strategies for AL Amyloidosis in an Era of Therapeutic Innovation

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Published:1st May 2023
Author: Dima D, Mazzoni S, Anwer F, Khouri J, Samaras C, Valent J, et al.
Availability: Free full text
Ref.:JCO Oncol Pract. 2023 May;19(5):265-275.
DOI:10.1200/OP.22.00396
Diagnostic and Treatment Strategies for AL Amyloidosis in an Era of Therapeutic Innovation


Despite significant progress and improving outcomes in the management of plasma cell disorders, AL amyloidosis remains diagnostically and therapeutically challenging for clinicians across practice settings. There is, however, a reason for optimism with the advent of new combination therapy approaches and novel targets offering the promise of improvement in end organ function, survival, and quality of life. This review offers a clinically applicable overview of an approach to diagnosis, risk stratification, and clinical management of AL amyloidosis in an era of rapid therapeutic innovation.


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