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Fibrinogen Deficiency in Bleeding Learning Zone

ISICEM 2019

Read time: 60 mins
Last updated:12th Aug 2024
Published:14th May 2020

In March 2019, experts from around the globe travelled to Brussels for the 39th International Symposium on Intensive Care and Emergency Medicine (ISICEM). Attracting more than 6,200 participants, ISICEM is dedicated to sharing the latest developments in critical care and emergency medicine. Video footage from the CSL Behring sponsored satellite symposium, featuring topics such as trauma induced coagulopathy and the critical reduction of fibrinogen, can be found below.

Professor Donat Spahn

Meet the expert

Donat Spahn is a Professor of Anaesthesiology and Chairman of the Institute of Anaesthesiology at University Hospital Zürich, Switzerland.

The elements of trauma induced coagulopathy

Professor Donat Spahn discusses the elements of trauma induced coagulopathy (TIC) from pre-existing conditions and co-morbidities to tissue damage and haemorrhage and the eventual critical reduction of coagulation factors, such as fibrinogen, through various mechanisms.

Coagulopathy is frequent after major trauma and fibrinogen becomes critically reduced first in many trauma patients. Watch to discover the elements of TIC from initial tissue damage to the critical reduction of coagulation factors.

Updates to the European guideline on the management of major bleeding following trauma

Announcing the launch of the 5th Edition of the European guideline on the management of major bleeding following trauma and noting new changes, Professor Donat R. Spahn shares new updates and stresses that compliance with this new guideline improves survival.

 

Professor Donat Spahn shares the new updates to the European guideline on the management of major bleeding highlighting. Learn how the new guidelines better reflect the decision-making process along the patient pathway and how they are now organised in a temporal sequence from a patient or problem-oriented perspective.

Key recommendations from the European guidelines of trauma management

Professor Donat Spahn summarises the key recommendations from the European guidelines of trauma management covering topics such as viscoelastic coagulation monitoring, antifibrinolytic agents, coagulation resuscitation, goal-directed coagulation algorithms and treatment with fibrinogen.


Learn how routine practice should include early and repeated monitoring of haemostasis. Also learn why tranexamic acid, an antifibrinolytic, should be administered as soon as possible and why fresh frozen plasma (FFP), pathogen-inactivated FFP or fibrinogen concentrate and red blood cells (RBC) should be used for the initial management of patients with massive haemorrhage.

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